brain

Temporal changes in the gene expression heterogeneity during brain development and aging (Research Article)
Cells in largely non-mitotic tissues such as the brain are prone to stochastic (epi-)genetic alterations that may cause increased …
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Temporal changes in the gene expression heterogeneity during brain development and aging (Research Article)
The widespread increase in inter-individual variability of gene expression in the human brain with age (Research Article)
Aging is broadly defined as a time-dependent progressive decline in the functional and physiological integrity of organisms. Previous …
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Gene expression-based drug repurposing to target aging (Research Article)
Aging is the largest risk factor for a variety of noncommunicable diseases. Model organism studies have shown that genetic and chemical …
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Gene expression-based drug repurposing to target aging (Research Article)
Gene expression reversal toward pre-adult levels in the aging human brain and age-related loss of cellular identity (Research Article)
It was previously reported that mRNA expression levels in the prefrontal cortex at old age start to resemble pre-adult levels. Such …
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Gene expression reversal toward pre-adult levels in the aging human brain and age-related loss of cellular identity (Research Article)