Publications

Ulas Isildak, H. Melike Dönertaş (2023). Evolutionary paths to mammalian longevity through the lens of gene expression (News & Views). EMBO J.

Gabriele Morabito, H. Melike Dönertaş, Luca Sperti, Jens Seidel, Aysan Poursadegh, Michael Poeschla, Dario Riccardo Valenzano (2023). Spontaneous onset of cellular markers of inflammation and genome instability during aging in the immune niche of the naturally short-lived turquoise killifish (Nothobranchius furzeri) (Research Article). BioRxiv.

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Hamit İzgi, DingDing Han, Ulas Isildak, Shuyun Huang, Ece Kocabiyik, Philipp Khaitovich, Mehmet Somel, H. Melike Dönertaş (2022). Inter-tissue convergence of gene expression during ageing suggests age-related loss of tissue and cellular identity (Research Article). eLife.

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Yasin Kaya, Tülay Karakulak, Cemil Can Saylan, E. Ravza Gür, Engin Tatlıdil, Sevilay Güleşen, Fatma Betül Dinçaslan, H. Melike Dönertaş (2022). Lessons from a ten-year-long journey: building a student-driven computational biology society across Turkey (Editorial Article). F1000 Research.

Wim L Cuypers, H. Melike Dönertaş, Jasleen K Grewal, Nazeefa Fatima, Chase Donnelly, Arvind Singh Mer, Spencer Krieger, Bart Cuypers, Farzana Rahman (2021). Highlights from the 16th International Society for Computational Biology Student Council Symposium 2020 (Editorial Article). F1000 Research.

Daniel K. Fabian, Matías Fuentealba, H. Melike Dönertaş, Linda Partridge, Janet M. Thornton (2021). Functional conservation in genes and pathways linking ageing and immunity (Review Article). Immunity & Ageing.

Etka Yapar, Ekin Saglican, H. Melike Dönertaş, Ezgi Özkurt, Zheng Yan, Haiyang Hu, Song Guo, Babür Erdem, Rori V. Rohlfs, Philipp Khaitovich, Mehmet Somel (2021). Convergent evolution of primate testis transcriptomes reflects mating strategy (Research Article). BioRxiv.

H. Melike Dönertaş, Daniel K. Fabian, Matías Fuentealba, Linda Partridge, Janet M. Thornton (2021). Common genetic associations between age-related diseases (Research Article). Nature Aging.

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Matías Fuentealba, Daniel K. Fabian, H. Melike Dönertaş, Janet M. Thornton, Linda Partridge (2021). Transcriptomic profiling of long- and short-lived mutant mice implicates mitochondrial metabolism in ageing and shows signatures of normal ageing in progeroid mice (Research Article). Mechanisms of Ageing and Development.

Daniel K. Fabian, H. Melike Dönertaş, Matías Fuentealba, Linda Partridge, Janet M. Thornton (2021). Transposable Element Landscape in Drosophila Populations Selected for Longevity (Research Article). Genome Biology and Evolution.

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Gülşah Merve Kılınç, Natalija Kashuba, Dilek Koptekin, Nora Bergfeldt, H. Melike Dönertaş, Ricardo Rodríguez-Varela, Dmitrij Shergin, Grigorij Ivanov, Dmitrii Kichigin, Kjunnej Pestereva, Denis Volkov, Pavel Mandryka, Artur Kharinskii, Alexey Tishkin, Evgenij Ineshin, Evgeniy Kovychev, Aleksandr Stepanov, Love Dalén, Torsten Günther, Emrah Kırdök, Mattias Jakobsson, Mehmet Somel, Maja Krzewińska, Jan Storå, Anders Götherström (2021). Human population dynamics and Yersinia pestis in ancient northeast Asia (Research Article). Science Advances.

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Ulas Isildak, Mehmet Somel, Janet M. Thornton, H. Melike Dönertaş (2020). Temporal changes in the gene expression heterogeneity during brain development and aging (Research Article). Scientific Reports.

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Sayane Shome, R Gonzalo Parra, Nazeefa Fatima, Alexander Miguel Monzon, Bart Cuypers, Yumna Moosa, Nilson Da Rocha Coimbra, Juliana Assis, Carla Giner-Delgado, H. Melike Dönertaş, Yesid Cuesta-Astroz, Geetha Saarunya, Imane Allali, Shruti Gupta, Ambuj Srivastava, Manisha Kalsan, Catalina Valdivia, Gabriel J Olguin-Orellana, Sofia Papadimitriou, Daniele Parisi, Nikolaj Pagh Kristensen, Leonor Rib, Marouen Ben Guebila, Eugen Bauer, Gaia Zaffaroni, Amel Bekkar, Efejiro Ashano, Lisanna Paladin, Marco Necci, Nicolás N Moreyra, Martin Rydén, Jordan Villalobos-Solís, Nikolaos Papadopoulos, Candice Rafael, Tülay Karakulak, Yasin Kaya, Yvonne Gladbach, Sandeep Kumar Dhanda, Nikolina Šoštarić, Aishwarya Alex, Dan DeBlasio, Farzana Rahman (2019). Global network of computational biology communities: ISCB's Regional Student Groups breaking barriers (Editorial Article). F1000 Research.

Zeliha Gözde Turan, Poorya Parvizi, H. Melike Dönertaş, Jenny Tung, Philipp Khaitovich, Mehmet Somel (2019). Molecular footprint of Medawar’s mutation accumulation process in mammalian aging (Research Article). Aging Cell.

Veronika R. Kedlian, H. Melike Dönertaş, Janet M. Thornton (2019). The widespread increase in inter-individual variability of gene expression in the human brain with age (Research Article). Aging.

H. Melike Dönertaş, Matías Fuentealba, Linda Partridge, Janet M. Thornton (2019). Identifying Potential Ageing-Modulating Drugs In Silico (Review Article). Trends in Endocrinology & Metabolism.

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Matías Fuentealba, H. Melike Dönertaş, Rhianna Williams, Johnathan Labbadia, Janet M. Thornton, Linda Partridge (2019). Using the drug-protein interactome to identify anti-ageing compounds for humans (Research Article). PLoS Computational Biology.

H. Melike Dönertaş, Matías Fuentealba, Linda Partridge, Janet M. Thornton (2018). Gene expression-based drug repurposing to target aging (Research Article). Aging Cell.

Gülşah Merve Kılınç, Dilek Koptekin, Çiğdem Atakuman, Arev Pelin Sümer, H. Melike Dönertaş, Reyhan Yaka, Cemal Can Bilgin, Ali Metin Büyükkarakaya, Douglas Baird, Ezgi Altınışık, Pavel Flegontov, Anders Götherström, İnci Togan, Mehmet Somel (2017). Archaeogenomic analysis of the first steps of Neolithization in Anatolia and the Aegean (Research Article). Proceedings of the Royal Society B.

Recep Ozgur Taskent, Nursen Duha Alioglu, Evrim Fer, H. Melike Dönertaş, Mehmet Somel, Omer Gokcumen (2017). Variation and functional impact of Neanderthal ancestry in Western Asia (Research Article). Genome Biology and Evolution.

H. Melike Dönertaş, Hamit İzgi, Altuğ Kamacıoğlu, Zhisong He, Philipp Khaitovich, Mehmet Somel (2017). Gene expression reversal toward pre-adult levels in the aging human brain and age-related loss of cellular identity (Research Article). Scientific Reports.

Gülşah Merve Kılınç, Ayça Omrak, Füsun Özer, Torsten Günther, Ali Metin Büyükkarakaya, Erhan Bıçakçı, Douglas Baird, H. Melike Dönertaş, Ayshin Ghalichi, Reyhan Yaka, Dilek Koptekin, Sinan Can Açan, Poorya Parvizi, Maja Krzewińska, Evangelia A Daskalaki, Eren Yüncü, Nihan Dilşad Dağtaş, Andrew Fairbairn, Jessica Pearson, Gökhan Mustafaoğlu, Yılmaz Selim Erdal, Yasin Gökhan Çakan, İnci Togan, Mehmet Somel, Jan Storå, Mattias Jakobsson, Anders Götherström (2016). The demographic development of the first farmers in Anatolia (Research Article). Current Biology.

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H. Melike Dönertaş, Sergio Martínez Cuesta, Syed Asad Rahman, Janet M. Thornton (2016). Characterising Complex Enzyme Reaction Data (Research Article). PLoS One.