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Evolutionary paths to mammalian longevity through the lens of gene expression (News & Views)
The natural variation in mammalian longevity and its underlying mechanisms remain an active area of aging research. In the latest issue …
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Evolutionary paths to mammalian longevity through the lens of gene expression (News & Views)
Inter-tissue convergence of gene expression during ageing suggests age-related loss of tissue and cellular identity (Research Article)
Developmental trajectories of gene expression may reverse in their direction during ageing, a phenomenon previously linked to cellular …
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Inter-tissue convergence of gene expression during ageing suggests age-related loss of tissue and cellular identity (Research Article)
Lessons from a ten-year-long journey: building a student-driven computational biology society across Turkey (Editorial Article)
The Regional Student Group Turkey (RSG-Turkey) is officially associated with the International Society for Computational Biology (ISCB) …
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Lessons from a ten-year-long journey: building a student-driven computational biology society across Turkey (Editorial Article)
Highlights from the 16th International Society for Computational Biology Student Council Symposium 2020 (Editorial Article)
In this meeting overview, we summarise the scientific program and organisation of the 16th International Society for Computational …
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Highlights from the 16th International Society for Computational Biology Student Council Symposium 2020 (Editorial Article)
Functional conservation in genes and pathways linking ageing and immunity (Review Article)
At first glance, longevity and immunity appear to be different traits that have not much in common except the fact that the immune …
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Functional conservation in genes and pathways linking ageing and immunity (Review Article)
Common genetic associations between age-related diseases (Research Article)
Age is a common risk factor in many diseases, but the molecular basis for this relationship is elusive. In this study we identified …
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Common genetic associations between age-related diseases (Research Article)
Transcriptomic profiling of long- and short-lived mutant mice implicates mitochondrial metabolism in ageing and shows signatures of normal ageing in progeroid mice (Research Article)
Genetically modified mouse models of ageing are the living proof that lifespan and healthspan can be lengthened or shortened, and …
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Transcriptomic profiling of long- and short-lived mutant mice implicates mitochondrial metabolism in ageing and shows signatures of normal ageing in progeroid mice (Research Article)
Transposable Element Landscape in Drosophila Populations Selected for Longevity (Research Article)
Transposable elements (TEs) inflict numerous negative effects on health and fitness as they replicate by integrating into new regions …
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Transposable Element Landscape in Drosophila Populations Selected for Longevity (Research Article)
Human population dynamics and Yersinia pestis in ancient northeast Asia (Research Article)
We present genome-wide data from 40 individuals dating to c.16,900 to 550 years ago in northeast Asia. We describe hitherto unknown …
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Human population dynamics and Yersinia pestis in ancient northeast Asia (Research Article)
Temporal changes in the gene expression heterogeneity during brain development and aging (Research Article)
Cells in largely non-mitotic tissues such as the brain are prone to stochastic (epi-)genetic alterations that may cause increased …
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Temporal changes in the gene expression heterogeneity during brain development and aging (Research Article)